Neurobiology of Disease Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction in a Mouse Model That Exhibits Age-Dependent Progression of Alzheimer’s Disease-Related Pathology
نویسندگان
چکیده
Adam D. Bachstetter,1 Christopher M. Norris,1,2 Pradoldej Sompol,1 Donna M. Wilcock,1,3 Danielle Goulding,1 Janna H. Neltner,1,4 Daret St. Clair,1,5,7 D. Martin Watterson,8 and Linda J. Van Eldik1,6 1Sanders-Brown Center on Aging, Departments of 2Molecular and Biomedical Pharmacology, 3Physiology, 4Pathology, 5Toxicology, and 6Anatomy and Neurobiology, and 7Markey Cancer Center, University of Kentucky, Lexington, Kentucky 40536, and 8Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611
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Cholinergic neuropathology in a mouse model of Alzheimer's disease
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